Use the following chart as a guide for not using certain powers in combination (or for deciding what powers to
use when playing "Forbidden Combo" style of play). Powers that do not appear on the chart can be used with
any other power. Powers with prohibitions against use with other powers are still in effect for use against
that other power, but the two can be used in combination unless they appear on the chart. An X indicates
that the powers should not be used together because of conflicting mechanics of inherent confusion or ambiguity.
A P indicates that the powers are abnormally powerful in combination and should probably not be used together.
A W indicates that one power partially steals the other's thunder and therfore the two should probably not be
used together. When two powers appear that should not be used together of against one another, use the first
one exposed and draw again for the second one.
Powers in italics are from the Internet.
| Amoeba | Entrepreneur (X) Macron (W) |
| Anti-Matter | Deuce (W) Gnome (W) Implosion (W) Phantom (W) Virus (X) Warpish (W) |
| Aristocrat | Doppelganger (W) |
| Arnold | Zombie (P) |
| Atrophy | Trader (W) |
| Aura | Mind (W) Visionary (P) |
| Berserker | Cult (X) Deuce (X) Empath (X) Pacifist (W) |
| Blitzkrieg | Deuce (W) |
| Boomerang | Dictator (P) Siren (P) |
| Busybody | Demon (P) Prophet (P) |
| Calculator | Oracle (P) |
| Cavalry | Parasite (P) |
| Chosen | Chronos (X) |
| Chronos | Chosen (X) |
| Clone | Machine (P) Miser (P) Pacifist (P) |
| Connoisseur | Doppelganger (X) |
| Counterfeiter | Empath (X) Ninja (X) Pacifist (X) |
| Crystal | Juggernaut (X) |
| Cult | Berserker (X) |
| Demon | Busybody (P) Paladin (X) Macron (X) |
| Deuce | Anti-Matter (W) Berserker (X) Blitzkrieg (W) Loser (W) |
| Dictator | Boomerang (P) Siren (W) |
| Doppelganger | Aristocrat (W) Connoisseur (X) Machine (P) Mesmer (P) Philanthropist (W) Prolong (W) Reserve (W) Wastrel (W) |
| Empath | Berserker (X) Counterfeiter (X) Pacifist (X) |
| Enigma | Laser (X) |
| Entrepreneur | Amoeba (X) |
| Filch | Machine (P) |
| Filth | Gorgon (W) Spiff (X) Toxin (W) |
| Fungus | Vampire (X) Void (X) Warpish (W) |
| Gambler | Silencer (P) |
| Gemini | Macron (P) |
| Ghost | Virus (P) Warpish (W) Zombie (W) |
| Gnome | Anti-Matter (W) |
| Gorgon | Filth (W) |
| Grief | Zombie (W) |
| Illuminati | Visionary (P) |
| Implosion | Anti-Matter (W) |
| Jaunt | Zombie (W) |
| Judge | Machine (P) |
| Juggernaut | Crystal (X) |
| Laser | Oracle (X) Enigma (X) Pavlov (X) Visionary (X) |
| Loser | Deuce (W) |
| Machine | Clone (P) Doppelganger (P) Filch (P) Judge (P) Mutant (P) Prolong (W) |
| Macron | Amoeba (W) Demon (X) Gemini (P) Phantom (P) Symbiote (P) |
| Mesmer | Doppelganger (P) Vulch (P) |
| Mind | Aura (W) Visionary (P) |
| Mirror | Oracle (P) |
| Miser | Clone (P) |
| Mutant | Machine (P) |
| Ninja | Counterfeiter (X) Empath (X) Pacifist (X) |
| Obverse | Oracle (P) |
| Oracle | Calculator (P) Laser (X) Mirror (P) Obverse (P) Sorcerer (P) |
| Pacifist | Berserker (W) Counterfeiter (X) Clone (P) Empath (X) |
| Paladin | Demon (X) |
| Parasite | Cavalry (P) Zombie (P) |
| Pavlov | Laser (X) Visionary (P) |
| Phantom | Anti-Matter (W) Macron (P) Virus (P) |
| Philanthropist | Doppelganger (W) |
| Prolong | Doppelganger (W) Machine (W) |
| Prophet | Busybody (P) |
| Reserve | Doppelganger (W) |
| Schizoid | Silencer (P) |
| Silencer | Gambler (P) Schizoid (P) |
| Siren | Boomerang (P) Dictator (W) Virus (P) |
| Sorcerer | Oracle (P) |
| Spiff | Filth (X) |
| Sting | Vacuum (W) Zombie (W) |
| Symbiote | Macron (P) Vacuum (P) Virus (P) |
| Toxin | Filth (W) |
| Trader | Atrophy (W) Visionary (P) Wastrel (W) |
| Vacuum | Sting (W) Symbiote (P) Zombie (W) |
| Vampire | Fungus (X) Void (W) |
| Virus | Anti-Matter (X) Ghost (P) Phantom (P) Siren (P) Symbiote (P) Warpish (P) |
| Visionary | Aura (P) Illuminati (P) Laser (X) Mind (P) Pavlov (P) Trader (P) |
| Void | Fungus (X) Vampire (W) |
| Vulch | Mesmer (P) |
| Warpish | Anti-Matter (W) Fungus (W) Ghost (W) Virus (P) |
| Wastrel | Doppelganger (W) Trader (W) |
| Zombie | Arnold (P) Ghost (W) Grief (W) Jaunt (W) Parasite (P) Sting (W) Vacuum (W) |